Last year I developed a rash under my eyes and I was promptly prescribed hydrocortisone cream. It didn't help much and the doctor referred me to see a dermatologist. I was told to keep using the hydrocortisone and I was discharged. As the steroid cream didn't help I searched the internet for another remedy and that's how I came across a product called Magicream. It claims it only contains natural ingredients and it promised to clear up my rash. I was so excited! I have recently found out that the cream in fact contains Clobetasol Propionate and Ketoconazole. I was devastated to find this out especially since side effects include red spots and a burning sensation! When I stopped using the cream the side effects were terrible - I don't need to tell you as you know how the withdrawal of steroid can affect ones face. I then did a search on line and found your website which made so much sense and helped me to understand what was happening with my skin. I ordered the Face & Body Wash and the Face & Neck TheraCream and I have been symptom FREE ever since. Thank you from a once frustrated person!! Trish Managold, UK
There are no tell, tell signs of steroid abuse like there are with recreational drugs and this can make true abuse a little difficult to spot. However, here at we want to look at all aspects of steroid use, and in doing so, give you a better understanding of the topic at hand. Some of what you find will be nothing new, but much of it promises to be information that you’ve never been told. There is so much to discuss when it comes to this topic, and we guarantee when it comes to steroid abuse you may very well find what you once believed will rapidly change once exposed to the truth.
Corticosteroids have been used as drug treatment for some time. Lewis Sarett of Merck & Co. was the first to synthesize cortisone, using a complicated 36-step process that started with deoxycholic acid, which was extracted from ox bile .  The low efficiency of converting deoxycholic acid into cortisone led to a cost of US $200 per gram. Russell Marker , at Syntex , discovered a much cheaper and more convenient starting material, diosgenin from wild Mexican yams . His conversion of diosgenin into progesterone by a four-step process now known as Marker degradation was an important step in mass production of all steroidal hormones, including cortisone and chemicals used in hormonal contraception .  In 1952, . Peterson and . Murray of Upjohn developed a process that used Rhizopus mold to oxidize progesterone into a compound that was readily converted to cortisone.  The ability to cheaply synthesize large quantities of cortisone from the diosgenin in yams resulted in a rapid drop in price to US $6 per gram, falling to $ per gram by 1980. Percy Julian's research also aided progress in the field.  The exact nature of cortisone's anti-inflammatory action remained a mystery for years after, however, until the leukocyte adhesion cascade and the role of phospholipase A2 in the production of prostaglandins and leukotrienes was fully understood in the early 1980s.