A lot of people use nasal sprays, but a lot of people use nasal sprays incorrectly. Just follow these simple steps and we’ll have you feeling better, faster. First, blow your nose to get the mucous out. Take a quick look down, like you’re reading a book. Now, use the opposite hand to nostril and insert the nozzle straight back and aim outward away from the middle part of your nose. Most doctors suggest just a spray or two. Then, switch hands and repeat on the other side. You don’t want to sniff or blow your nose immediately after using your medicine. You’ll lose the good stuff that needs to stay put!
Mortuaire, G., de Gabory, L., François, M., Massé, G., Bloch, F., Brion, N., ... Serrano, E. Rebound congestion and rhinitis medicamentosa: Nasal decongestants in clinical practice. (2013, June 1). Critical review of the literature by a medical panel. European Annals of Otorhinolaryngology, Head and Neck Diseases , 130(3), 137-144. Retrieved from https:///#!/content/playContent/1--S1879729612001378?returnurl=http:%2F%%2Fretrieve%2Fpii%2FS1879729612001378%3Fshowall%3Dtrue&referrer=https:%2F%2F .
In a pharmacokinetic study comparing flunisolide nasal solution (flunisolide nasal spray .025%) (29 mcg per spray) with flunisolide nasal solution (flunisolide nasal spray .025%) (25 mcg per spray), the original formulation, the two formulations were not bioequivalent. The total absorption of flunisolide nasal solution (29 mcg per spray) was 25% less than that of flunisolide nasal solution (25 mcg per spray), and the peak plasma concentration was 30% lower. The clinical significance of these differences is likely to be small, particularly since clinical efficacy is attributable to a local effect on nasal mucosa (see Pharmacodynamics ).